Mastercard is expanding its settlement capabilities to include on-chain transactions using regulated U.S. dollar stablecoins.

This initiative operates alongside existing fiat processes to provide financial institutions with enhanced liquidity management. The system enables settlements during weekends and holidays to support 24/7 finance.

Mastercard will initially support Circle’s USDC, PayPal’s PYUSD, Ripple’s RLUSD, and SoFi’s SoFiUSD. These stablecoins will function across the Ethereum, Solana, Polygon, and Base blockchain networks.

Initial launch partners include Cross River, Lead Bank, and Nuvei.