Iovance Biotherapeutics is trading at $12.15, up 10.55% in pre-market, with no clear catalyst identified. - No company-specific announcement or confirmed catalyst for September 29, 2026, has been identified; recent coverage focused on its pipeline and prior results, not a new overnight event. - Major indices showed modest gains, but no broad move above 0.5% clearly explains the sharp rise; the pre-market jump’s cause remains unclear.