Advanced Micro Devices Inc. (AMD) and Oracle announced an expanded partnership for AI infrastructure on October 14, 2025. As part of the collaboration, Oracle will deploy 50,000 of AMD's upcoming MI450 GPUs in its cloud infrastructure, with the initial deployment scheduled to begin in the third quarter of 2026 and further expansion planned for 2027 and beyond. The partnership aims to build a massive AI 'supercluster' to meet the demands of next-generation AI models. Following the announcement, AMD's shares saw a 3% increase in premarket trading.